Antimicrobial Agents
نویسندگان
چکیده
Use of Nonlinear Mixed-Effects Analysis for Improved Precision of Early Pharmacodynamic Measures in Tuberculosis Treatment Geraint R. Davies,* Richard Brindle, Saye H. Khoo, and Leon J. Aarons Wellcome Trust Centre for Clinical Tropical Medicine, University of Liverpool, Liverpool, United Kingdom; Department of Clinical Microbiology, Portsmouth Hospitals, Portsmouth, United Kingdom; Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, United Kingdom; and School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, United Kingdom
منابع مشابه
Antimicrobial susceptibility of one thousand bacterial isolates to five antibacterial agents commonly used in the Iranian poultry industry
BACKGROUNDS: Different susceptibility rates of pathogenic bacteria to antimicrobial agents are considered major factors in the choice of drugs and the success of treatments. Concerns have been raised regarding the emergence of antimicrobial resistance among pathogenic bacteria that may result in unpredictable antimicrobial susceptibilities and therapy failure. OBJECTIVES: The purpose of this in...
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Introduction: Although bacteria producing biofilm are more resistance to antimicrobial agents, biofilm formation can stimulated by sub-minimal inhibitory concentrations (sub-MICs) of some antimicrobial agents. Therefore, we designed present study to investigate the in vitro efficacy of several antibiotics (including ceftazidime, piperacillin, ticarcillin, carbenicillin, aztreonam, merop...
متن کاملSynthesis of Isoxazoles and Cyanopyridines Bearing Benzo(b)thiophene Nucleus as Potential Antitubercular and Antimicrobial Agents
Isoxazole (2a-l) and cyanopyridine (3a-l) derivatives have been prepared by condensing chalcones (1a-l) with hydroxylamine hydrochloride and malononitrile respectively. While compounds 1a-l have been synthesized by the reaction of p-(3’-chloro-2’-benzo(b)thiophenoylamino)-acetophenone with different aldehydes. All the compounds were screened for their antitubercular and antimicrobial activities...
متن کاملSyntheses of Substituted 1,3,4-Oxadiazole, 1,3,4-Thiadiazole and 1,2,4-Triazole Derivatives as Potential Antimicrobial Agents
A series of 2-(4-nitro-1-imidazolylmethyl)-1,3,4-oxadiazole, 1,3,4-triazole and 3-(4-nitro-1-imidazolylmethyl)-1,2,4-triazole derivatives were synthesized and tested for their antimicrobial activity. Some of the tested compounds were active against Staphylococcus aureus, Staphylococcus epidermidis, Bacillus subtilis, Clostridium difficile, Aspergillus niger and Cryptococcus neoformans.
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Reaction of 2-hydrazinocarbonyl-3-chloro-5-phenoxy-benzo[b] thiophene with different substituted phenyl isothiocyanate gave N-substituted arylthiosemi-carbazide derivatives (1a-h). 1,3,4-Thiadiazole derivatives (2a-h) were prepared by the cyclization of arylthiosemicarbazides (1a-h) with concentrated sulphuric acid. All the compounds were screened for their antitubercular activity against Mycob...
متن کاملEvaluation of Antioxidant and Antimicrobial Effects of Chamomile (Matricaria chamomilla L.) Essential Oil on Cake Shelf Life
Background: Essential oils of medicinal plants such as chamomile are very complex natural mixtures which can contain compounds at quite different concentrations and some of their components have antioxidant and antimicrobial activities in foodstuff. Objective: The antioxidant and antimicrobial effects of chamomile essential oil in cake preparation were evaluated during 75 days of storag...
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